By Ch.W. Sensen, Benedikt Hallgrimsson
This booklet makes an attempt for the 1st time to supply an summary of the main ways to organic and clinical imaging, the techniques for snapshot research and the construction of types, that are in accordance with the result of picture research. This units the ebook other than the standard monographs, which introduce the reader simply to a unmarried expertise. Given the large variety of themes lined, this publication presents an outline of the sphere, that is worthwhile for a large viewers, from physicians and biologists to readers who wish to recognize extra concerning the know-how, that is used to derive diagnoses of ailments this present day.
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Extra info for Advanced Imaging in Biology and Medicine: Technology, Software Environments, Applications
Neuroimage 37:530–538 de Zwart JA, van GP, Golay X, Ikonomidou VN, Duyn JH (2006) Accelerated parallel imaging for functional imaging of the human brain. NMR Biomed 19:342–351 Di MM, Sadun C, Port M, Guilbert I, Couvreur P, Dubernet C (2007) Physicochemical characterization of ultrasmall superparamagnetic iron oxide particles (USPIO) for biomedical application as MRI contrast agents. Int J Nanomedicine 2:609–622 Dijkhuizen RM (2006) Application of magnetic resonance imaging to study pathophysiology in brain disease models.
Pharmacological fMRI (phMRI) which uses fMRI to determine regional effects of drugs on the brain, is another growing application of this technology in preclinical drug testing (Borsook et al. 2006; Dijkhuizen 2006; Negus et al. 2006). , its combination with other techniques such as optical or electrophysiological measures in order to better understand the physiological basis of fMRI and its interpretation with respect to altered neuronal activity (Colonnese et al. 2008; Huttunen et al. 2008; Logothetis et al.
2007). Molecular imaging using magnetic nanoparticles will likely also prove a useful tool for monitoring stem cell migration and therapies (Magnitsky et al. 2007). In addition to detecting early stages of the disease process, nanoparticles may be designed to also deliver treatment in the future. Finally, future integration of molecular imaging into the process of drug development can be anticipated to facilitate the preclinical evaluation of targeted drug treatments. Acknowledgments The author thanks D.